Importantly, although the difference did not reach statistical significance due to the large intra-group variance (P>0.05), basal plasma levels of interleukin-6 were 51% higher in adrenalectomized mice (217±43 pg/ml; N=11) as compared to SHAM-operated controls (144±37 pg/ml; N=12).
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Leukocytosis and enhanced susceptibility to endotoxemia but not atherosclerosis in adrenalectomized APOE knockout mice.
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