Interestingly, even though they did not reach statistical significance, moderate fold-change reductions of IL-13 anti-inflammatory cytokine levels were observed in the cases of stimulation of primed microglia with the TLR7 agonists Imiq and ssRNA40 ( Figure 1A ) .
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Preconditioning of microglia by α-synuclein strongly affects the response induced by toll-like receptor (TLR) stimulation.
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