These elevated levels of fusion-related as well as maturation-related osteoclastic genes (cathepsin K and RANK were significantly upregulated, whereas TRAP showed a clear trend for higher expression in resorbing compared to nonresorbing osteoclasts) make it impossible to assign the material-dependent effect to either a pure cell fusion-specific or a pure resorption-specific effect.
← all excerpts
Osteoclasts on bone and dentin in vitro: mechanism of trail formation and comparison of resorption behavior.
1
—
—