Mechanical load modulates chondrogenesis of human mesenchymal stem cells through the TGF-beta pathway.

J Cell Mol Med · 2010 · PMC3828850 · PMID 19432813

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In all the three groups where samples were cultured in medium with different concentrations of TGF-β 1 , the total GAG/DNA value showed a trend of up-regulation by mechanical load, this difference was significant in the groups with 0 ng/ml ( P < 0.001) or 10 ng/ml TGF-β 1 ( P < 0.05).

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