Efficacy of micronutrient supplementation on skin aging and seasonal variation: a randomized, placebo-controlled, double-blind study.

On the other hand, on the exposed skin area, which is more prone to seasonal changes, the protective effect of the oral supplement was highly significant in the active group ( Figure 7 ).

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Subject self-assessment The self-assessment questionnaire revealed a positive increase in elasticity and firmness and a decrease in roughness and dryness in the active group; however this did not reach statistical significance.

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