Predictive modeling for diagnostic tests with high specificity, but low sensitivity: a study of the glycerol test in patients with suspected Menière's disease.

PLoS One · 2013 · PMC3832512 · PMID 24260193

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quite significantno p-value reported

For a benefit of 10, the optimal strategy would be to test almost every patient, because the missed benefit from a false-negative decision represents a quite significant loss.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.