A clear trend towards an inhibition of migration capability was also observed for U-2OS/DX580, Saos-2, and Saos-2/DX580, whereas IOR/OS18, U-2OS, and U-2OS/MTX300 did not show any response to VX-680 treatment ( Supplementary Figure S2A ).
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Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma.
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