With regard to other previously reported loci, associations with total and HMW adiponectin levels reached genome-wide significance for ADIPOQ (rs10937273), and we observed nominally significant associations for GPR109A (rs601339), CMIP (rs2925979), and PEPD (rs731839) ( Supplementary Table 2 ).
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Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations.
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