EGF receptor and COX-1/COX-2 enzyme proteins as related to corresponding mRNAs in human per-operative biopsies of colorectal cancer.

BMC Cancer · 2013 · PMC3840662 · PMID 24171795

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

showed a trendp < 0.07so close (0.05 < p ≤ 0.1)

COX-EGFR Regression analysis between COX-1 mRNA and EGFR mRNA showed a trend to significance in tumor tissue (p < 0.07).

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a weak trendno p-value reported

Similarly, COX-2 mRNA was not significantly increased in tumor tissue versus mucosa tissue, which confirms our previous results [ 12 ], although there was a weak trend to increased COX-2 mRNA across tumor progression.

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highly significantno p-value reported

These important observations with different molecular size patterns of variable COX-2 proteins in tumor and mucosa tissues may be highly significant but must await further analytical evaluations.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.