Febrile temperatures unmask biophysical defects in Nav1.1 epilepsy mutations supportive of seizure initiation.

J Gen Physiol · 2013 · PMC3840920 · PMID 24277604

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showed a trendno p-value reported

Compared with WT, R865G showed a trend toward a reduction in sodium current density at physiological temperature and a significant reduction at voltages −10 to 30 mV at 40°C ( Fig. 1, E and F ).

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