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The gastric CB1 receptor modulates ghrelin production through the mTOR pathway to regulate food intake.

PLoS One · 2013 · PMC3841176 · PMID 24303008

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As rimonabant treatment, gastric phospho-S6K1 responded to AM281 treatment in a manner similar to that pmTOR, although the phospho-S6K1 response did not reach statistical significance (control: 100 vs AM281: 116.71±9.04 pS6K1/S6K1; no significant difference, Figure 8B ).

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