Comorbid diseases as predictors of survival of primary total hip and knee replacements: a nationwide register-based study of 96 754 operations on patients with primary osteoarthritis.

In some disease groups, the effect on survival rates was clinically highly significant, which may impair the cost-effectiveness of joint replacements in affected individuals.

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The effect of neurodegenerative diseases was slighter ( figure 4 D) and did not reach statistical significance ( table 2 ).

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