Barely Significant
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Renal replacement therapy in ADPKD patients: a 25-year survey based on the Catalan registry.

BMC Nephrol · 2013 · PMC3844422 · PMID 24007508

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hugely significantno p-value reported
The hugely significant genetic factor in ADPKD could be related to a fatal renal prognosis that is quite difficult to modify with the currently available therapeutic tools which improve cardiovascular factors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.