“hugely significant”

A hugely significant decrease in IL-17a secretion(+ 90%, p < 0.05), followed by decreases in IFN-γ (–76%, p < 0.05), IL-12 (–60%, p < 0.05) and IL-23 (–46%, p < 0.05) were observed in stimulated PBMCs cultured with Rooibos extract in comparison to untreated PBMCs.

These trends are hugely significant for sustainability, beyond the subset of people who have moved involuntarily.

The case fatality rate of SA-AKI is high, and thus, predicting the risk of SA-AKI-related death is hugely significant.

Yet there is a hugely significant difference between the two scenarios.

Disaster damage data are hugely significant to support disaster risk reduction decisions and public health promotion.

Understanding levels of satisfaction or otherwise for victim-survivors and perpetrators is hugely significant when attempting to measure success in evaluations of new processes, yet identifying the best way to do this is complex.

To a young child or adolescent who is leading a normal, healthy and active life; to be suddenly knocked off balance, almost by something out of nowhere, something which potentially renders you unable to move, was hugely significant for all of the participants.

Either way, the situation in January 1st 2022 showed a hugely significant difference from the situation on January 1st 2020.

The role that tech companies play in the context of AI technologies is hugely significant and the subject of a number of emerging research endeavours focusing, inter alia, on Big Tech. 46 The theme of investigating private authority in global governance is not new in IR but started as an analytical concern in the late 1990s. 47 What appears to be new, however, is the status of such tech companies as contributors to shaping international governance of AI in explicit and implicit ways. 48 Explicitly, we see that many state actors or international organisations seek out tech company representatives to participate in AI governance conversations.

Nevertheless, it was nowhere near the proportion of the intensity of the psychic income which is associated with the single good case, the great result from an individual case, and the great amount of psychic income after a well-done repair of a cleft lip or palate, particularly on the FMP; which is a dramatic result, hugely significant to the patient's life, and provides sustainability through education and by providing for succession.

1 , 2 An absolute improvement of 5 points in score could lead to a 30-point increase in percentile rank, which is hugely significant for hospital administration, showing that these results have both statistical and real-world impact.

“I have felt lonely and I think touch is hugely significant and the fact that when I see my friends or relatives I can’t give them a hug you know, particularly because I live on my own, it’s quite, it’s really depressing”.

It has been further complicated in the last decade with the hugely significant emergence of a consensus on rating the quality of a whole evidence base for each outcome through the use of Grading of Recommendations, Assessment, Development and Evaluations (GRADE). 5 For individual RCTs, quality is typically described as ‘design and RCT conduct, to prevent systematic errors, or

The large time comparisons (15/20 min–24 h) observed between REIMS and PCR to determine the species of six mislabelled samples are hugely significant.

Whether a parasite has entered mitosis or not is obviously a hugely significant event in the context of cell biology, but in a mononucleated parasite this could only be determined using immunofluorescence microscopy with cell cycle or DNA replication markers. 1.

The successful differentiation would be hugely significant with regards to corneal transparency in vivo and in vitro .

The p-value obtained from the chi-squared test was hugely significant, registering at 9.13 × 10−8, thereby reinforcing the validity of our findings.

Increases in blood pressure during isometric/resistance exercise can be hugely significant and far exceed expected pressures, with one landmark study showing systolic blood pressures (invasive brachial pressure) surpassing 320 mmHg during double leg press [ 11 ].

The consequences of this for the regulation of these systems is potentially hugely significant, as the rights and obligations for personal data differ strongly from the few generally thought applicable to models.

The paid ASC workforce is comparatively small, but still hugely significant, amounting to 1.59 million workers (Skills for Care, 2024a , p. 15), the largest figure ever recorded (Skills for Care, 2024a , p. 29).

Studying concrete permeability is therefore hugely significant because it is closely connected to the penetration of water, which reduces the pH value of the pore fluid and carries harmful ions, resulting in degradation and loss of mechanical strength.

Among the 10 dimensions describing mental health status, there were significant differences in the scores of students' subjective awareness of family economic status in the seven dimensions of somatization, depression, anxiety, terror, delusion, psychosis, and others, among which the difference in the scores of somatization dimension was hugely significant.

However, due to the hugely significant variation in climatic conditions on a geographical basis, asphalt materials need to be selected carefully in order to increase the longevity and lifespan of the road pavement thus reducing the possible huge cost of road maintenance [ 1 ].

In response to Ant 4 treatment, HL-60 cells showed a hugely significant decrease in glutathione content compared with the controls at each 24 h time point after addition of Ant 4 ( Figure 6 ).

While the study by Friedrich and Müller-Goymann illustrated an increased drug loading with higher phospholipid concentrations (e.g., 50%), it has also been demonstrated that this difference may not be hugely significant, e.g., in the work of Chime et al.