showed a trendp = 0.07
Sub-group analyses stratified by HIV status showed a trend towards a protective effect of high-dose VAS on cough and rapid respiratory rate for HIV-infected children [RR 0.54 (0.24-1.20), p = 0.07], while children without HIV infection were at increased risk for these conditions [RR 1.47 (1.16-1.86), p = 0.001].