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Population Pharmacokinetics of Lumefantrine in Pregnant and Nonpregnant Women With Uncomplicated Plasmodium falciparum Malaria in Uganda.

CPT Pharmacometrics Syst Pharmacol · 2013 · PMC3852159 · PMID 24226803

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showed a trendno p-value reported
The bootstrap diagnostics of the full covariate model ( Figure 2 ) showed a trend toward lower peripheral volume of distribution during pregnancy, but this covariate did not contribute to a significant improvement of the model.

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