Several other cytokines (IL-6, IL-8, RANTES, MCP-1α, MIP-1α, IFN-γ, and IFN-β) showed a trend of increased expression with intranasal inoculation of HEp-2-grown M37 and additional animals would likely clarify these trends.
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Human respiratory syncytial virus Memphis 37 grown in HEp-2 cells causes more severe disease in lambs than virus grown in Vero cells.
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