Interestingly, the firing rate of GnRH neurons tended to increase rather than decrease (by 70.5 ± 21.9%), although this effect did not reach statistical significance (NK test, P = 0.071, Kyn+Bic+WIN vs.
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Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons.
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0.0710
0.0710