An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool.

PLoS Genet · 2013 · PMC3861205 · PMID 24348261

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0.1400

closest p · 2.8× alpha

0.1400

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The sentences

did not reach statistical significancep-value = 0.14not close (p > 0.1)

En1::Cre;Lmx1bcKO embryos showed a reduction of miR135a , although this change did not reach statistical significance (n = 5 controls, 3 mutants; control mean = 1±0.05, mutant mean = 0.81±0.02; p-value = 0.14).

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