Although the difference did not reach statistical significance for the individual time-points, ESAT-6 gave a statistical significant protection in the overall experiment (Mann-Whitney U-test: ESAT-6 vaccinated compared to control group: week 37 p.i. p=0.0541, week 49 p.i. p=0.1893, overall experiment p=0.0168).
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ESAT-6 (EsxA) and TB10.4 (EsxH) based vaccines for pre- and post-exposure tuberculosis vaccination.
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