Although the elastin gene only showed a trend of age-related decline (not significant), critical microfibril components (such as fibrillin-1 and MAGP-1), as well as “tethering” proteoglycans (such as biglycan and decorin), and elastic fiber and cell interface molecules (such as fibulin-5) had significantly lower levels of expression in aged skin.
← all excerpts
Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study.
1
—
—