Grading breast cancer tissues using molecular portraits.

Mol Cell Proteomics · 2013 · PMC3861711 · PMID 23982162

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a clear trendno p-value reported

A clear trend involving both up- and down-regulated proteins could be observed with increasing histological grade.

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an increasing trendno p-value reported

For example, cyclin-dependent kinase 1 (CDK1), minichromosome maintenance complex component 3 (MCM3), DNA replication licensing factor MCM7, ATP-citrate synthase, polyadenylate-binding protein 4, and 6-phosphofructokinase type C displayed an increasing trend and were most up-regulated in grade 3 tumors ( Fig. 2 and supplemental Fig.

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