Inferior frontal gyrus preserves working memory and emotional learning under conditions of impaired noradrenergic signaling.

However, the treatment × load interaction effect failed to reach statistical significance [ F (2, 33) = 3.46, p > 0.05], indicating that there was no load-specific effect of PRO (Table 2 ; Figure 2B ). fMRI data—working memory In line with previous fMRI studies using spatial working memory paradigms (Wager and Smith, 2003 ; Rottschy et al., 2012 ) we found increased activity in the fronto-parietal working memory networks for both working memory contrasts (“load 3 > load 1”; “load 5 > load 1”) (see also Table 3 for the main effect of WM load).

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