Despite having a lower performance compared to WTs at this task, male R6/1s did not reach statistical significance ( Figure 2A ), whereas, female R6/1s were significantly impaired versus WTs (p<0.001, Figure 2B ).
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Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the R6/1 mouse model of Huntington's disease.
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