Barely Significant
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Stereoselectively fluorinated N-heterocycles: a brief survey.

Beilstein J Org Chem · 2013 · PMC3869242 · PMID 24367435

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a clear trendno p-value reported
This explains why the K i values in Figure 11 do not seem to follow a clear trend: the quoted K i values were all measured at the same pH, whereas it would be more revealing to consider the K i of each molecule at its “optimal” pH.

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