The thermal profile of MBP-E6 in assay buffer compared to DMSO (1.8% v/v) revealed that DMSO shifted the Tm of MBP-E6 from 59.38 ± 0.13°C to 59.0 ± 0.0°C ( Figure 10A ), which failed to reach statistical significance.
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Structure based identification and characterization of flavonoids that disrupt human papillomavirus-16 E6 function.
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