Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.

aureus , although these differences did not reach statistical significance ( Figure 5 , Figure S3 ), which correlated with enhanced chemokine expression ( Figure 4 ). sarA Mutation Leads to Decreased α-toxin Production during CNS Catheter-Associated Infection Prior studies have reported decreased α-toxin production by certain S. aureus USA300 sarA mutant strains in vitro and in vivo [13] , [21] , [22] .

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