Promoter DNA methylation regulates progranulin expression and is altered in FTLD.

Acta Neuropathol Commun · 2013 · PMC3893557 · PMID 24252647

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highly significantno p-value reported

As shown in Figure 2 b, treatment with 0.5 μM DAC over 9 days led to a progressive highly significant 11-fold increase in GRN mRNA expression in LCL #3.

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showed a trendno p-value reported

DNMT3b levels showed a trend towards increased expression, not reaching statistical significance (Figure 5 c).

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