Furthermore, while the instillation of 50 μg PVP-AgNP caused a slight increase (17-fold) in the number of neutrophils that did not reach statistical significance, the instillation of 250 μg PVP-AgNP produced a significant influx (60-fold) of neutrophils into the lungs ( Figure 7 ).
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Cytotoxic and proinflammatory effects of PVP-coated silver nanoparticles after intratracheal instillation in rats.
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