A significant response to sunitinib in a patient with anaplastic thyroid carcinoma.

Despite the fact that only 80 of 180 planned patients were recruited (due to a slow recruitment rate), a strong trend in improved overall survival was observed; 5.2 months versus 4.0 months for the CA4P and control arm respectively (Hazard Ratio 0.95:95% CI, 0.38-1.10).[ 5 ] Nagaiah et al . reported the treatment of 16 metastatic ATC patients with sorafenib.[ 6 ] Two (13%) out of 15 evaluable patients achieved partial response by Response Evaluation Criteria In Solid Tumors (RECIST) criteria, however, median progression free survival was only 1.9 months (95% CI: 1.7-4.1) and median overall survival was 3.9 months (95% CI: 2.7-7.1).

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