In addition, multivariate analysis and Cox regression combining Ann Arbor Stage revealed that PRDM1 expression status did not reach statistical significance as an independent predictor of 5-year OS ( P = 0.556) and FFS ( P = 0.727), but Ann Arbor Stage was an independent predictor of 5-year OS ( P = 0.002) and FFS ( P = 0.003).
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The downregulation of PRDM1/Blimp-1 is associated with aberrant expression of miR-223 in extranodal NK/T-cell lymphoma, nasal type.
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