Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling.

Moderately differentiated and PD tumours themselves form weaker clusters ( P =0.05 and P =0.06, respectively), however when combined they show a highly significant clustering pattern ( P =0.002).

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The cluster containing only cSCC included 73% (11 out of 15) of the MD–PD tumours, compared with 40% (6 out of 15) of the WD tumours, although this difference did not reach statistical significance using a two-tailed Fisher's exact test.

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