Decreased expression of PTPN12 correlates with tumor recurrence and poor survival of patients with hepatocellular carcinoma.

PLoS One · 2014 · PMC3901655 · PMID 24475046

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0510

boldest claim

The sentences

highly significantP <0.001actually significant

In Kaplan–Meier survival analysis, a highly significant association of decreased PTPN12 expression with shortened patient survival was revealed in HCC patients ( Figure 3A, P <0.001, Kaplan-Meier method).

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a significant trendP <0.001actually significant

Patients with decreased PTPN12 expression also showed a significant trend toward worse recurrence-free survival compared to that with normal PTPN12 expression (hazard ratio: 0.518, 95% CI: 0.366–0.733, P <0.001, Table 2 , Cox regression model; Figure 3D , Kaplan-Meier method).

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a strong tendency towards statistical significanceP = 0.051so close (0.05 < p ≤ 0.1)

In addition, a strong tendency towards statistical significance ( P = 0.051, Table 1 ) has been found between PTPN12 expression and the serum AFP levels.

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