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Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.

BMC Cancer · 2014 · PMC3903446 · PMID 24444383

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Although the median value of sensitivity of ER-negative breast cancer cells was higher than that of ER-positive cells, the difference between these two subtypes did not reach statistical significance (Figure 2 B).

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