Comparable long-term efficacy of Lopinavir/Ritonavir and similar drug-resistance profiles in different HIV-1 subtypes.

PLoS One · 2014 · PMC3903498 · PMID 24475093

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did not reach statistical significanceno p-value reported

While such associations did not reach statistical significance in each of the studies alone, pairwise-association analysis of all 101 C genotypes from LPV/r treatment-failing patients in the two studies together revealed a strong positive association trend between M46I and I54V ( p = 0.06 , Fisher's two-tailed Exact Test) and between I54V and V82A ( p = 0.09 ).

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