After the reporting of the 50% survival data, which showed a trend in favor of 500mg over 250mg, it was agreed to perform a final survival analysis after 75% of patients had died.
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Final overall survival: fulvestrant 500 mg vs 250 mg in the randomized CONFIRM trial.
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The sentences
The OS analysis suggested a numerical trend in favor of 500mg over 250mg despite the lack of a statistically significant difference ( 9 ).