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The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.

PLoS One · 2014 · PMC3907505 · PMID 24498043

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Linoleoylcarnitine (150 μM) also slightly increased H 2 O 2 release, but this did not reach statistical significance ( Figure 4B ).

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