Comprehensive interrogation of CpG island methylation in the gene encoding COMT, a key estrogen and catecholamine regulator.

BMC Med Genomics · 2014 · PMC3910242 · PMID 24460628

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showed a trendno p-value reported

Further work investigating the functional consequences of such methylation is needed, although our gene expression data showed a trend toward decreased COMT expression with increasing methylation.

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