Barely Significant
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Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection.

PLoS Pathog · 2014 · PMC3911819 · PMID 24497824

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a positive trendno p-value reported
We also observed a positive trend between CXCR5 high PD-1 high cells and serum concentrations of soluble CD14.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.