Barely Significant
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Matrix metalloproteinase-2, tissue inhibitor of matrix metalloproteinase-2, and transforming growth factor beta 1 in the aqueous humor and serum of patients with pseudoexfoliation syndrome.

Clin Ophthalmol · 2014 · PMC3913541 · PMID 24511224

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Serum levels of TIMP-2 were elevated in patients with PEX syndrome compared with patients with cataract, but the difference did not reach statistical significance.

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highly significantno p-value reported
Schlötzer-Schrehardt et al 3 studied aqueous samples from patients with PEX syndrome and PEX glaucoma and showed a highly significant increase in total MMP-2 and TIMP-2 compared with samples from patients with cataract.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.