Barely Significant
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Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.

Genetics · 2014 · PMC3914625 · PMID 24281154

Europe PMCDOI
1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

nearly significantP = 0.08so close (0.05 < p ≤ 0.1)
Although we did not observe a significant difference in the mRNA levels of the upstream regulators of the UPR [IRE1, PEK (PERK), Hsc70-3 (BiP; GRP78), and XBP1] in the GeneChip analysis, a more sensitive analysis by qRT-PCR in male eye imaginal discs expressing mutant hINS compared to the GMR-Gal4 control revealed significant increases in expression of PERK (CG2087), BiP (CG4147), and XBP1 (CG9415) and a nearly significant increase in expression of IRE1 (CG4583; P = 0.08) ( Table S5 ).

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