Seven CHD candidate genes, including EGFR, EVC2, NFATC2, NR2F2, TBX5, CFC1B and GJA5 , were chosen for further validation in a larger number of TOF cases because of their nominally significant differences in methylation levels and the important roles they play in the development of the heart.
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Association of promoter methylation statuses of congenital heart defect candidate genes with Tetralogy of Fallot.
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