Azilsartan, an angiotensin II type 1 receptor blocker, restores endothelial function by reducing vascular inflammation and by increasing the phosphorylation ratio Ser(1177)/Thr(497) of endothelial nitric oxide synthase in diabetic mice.

Cardiovasc Diabetol · 2014 · PMC3916073 · PMID 24485356

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did not reach statistical significanceno p-value reported

Although changes in phosphorylation signals either at Ser 1177 or Thr 495 did not reach statistical significance, the ratio of phosphorylation at Ser 1177 to phosphorylation at Thr 495 was statistically significantly lower in KKAy mice (Figure 3 ).

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