Barely Significant
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The expression of multiple proteins as prognostic factors in colorectal cancer: cathepsin D, p53, COX-2, epidermal growth factor receptor, C-erbB-2, and Ki-67.

Gut Liver · 2014 · PMC3916682 · PMID 24516696

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They reported that COX-2 expression was the only significant prognostic factor while the traditional TNM staging did not reach statistical significance.

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