Evaluation of the Effects of Atorvastatin on the Treatment of Secondary Pulmonary Hypertension due to Chronic Obstructive Pulmonary Diseases: A Randomized Controlled Trial.

Iran Red Crescent Med J · 2013 · PMC3918187 · PMID 24578830

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did not reach statistical significanceno p-value reported

A trend towards a decrease in PH level was observed in the statin group, but it did not reach statistical significance.

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a positive trendno p-value reported

Considering findings of previous studies and such a positive trend in our study towards statin benefits in PAH treatment of COPD patients, Although we cannot come in conclusion that the addition of statins to the treatment of patients with PAH as an adjuvant therapy to current treatment for PAH is safe and well tolerated with definite advantages, we can suggest that more developed RCTs with adequate sample size may prove such effect of statins and open a new window for physicians towards COPD treatment and for patients towards higher life quality.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.