Chronic exposure to a gambling-like schedule of reward predictive stimuli can promote sensitization to amphetamine in rats.

Of the lower order polynomial trends (linear, quadratic, cubic) only the three-way interaction for the linear trend approached significance, F (4, 19) = 2.32, p = 0.094, reflecting the generally monotonic increase in nose pokes over sessions in group 75 and relatively more rapid stabilization at high, intermediate, and low levels of responding in the other groups when the CS was present.

also in 8,237 other papers

The marginally significant effect of the covariate for the CS absent condition in the ANCOVA of locomotor responses to 1 mg/kg AMPH suggests that the tendency toward premature drug-free responding explained some of the variability in locomotor effects of AMPH during the sensitization sessions.

also in 26,082 other papers