The total number of circulating white blood cells tended to be higher in the GM-CSF–treated group but did not reach statistical significance; the proportion of neutrophils and monocytes was, however, greater in the GM-CSF–treated mice ( Tables 1 and 2 ).
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Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
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