PIK3CA mutations frequently coexist with EGFR/KRAS mutations in non-small cell lung cancer and suggest poor prognosis in EGFR/KRAS wildtype subgroup.

PLoS One · 2014 · PMC3922761 · PMID 24533074

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did not reach statistical significanceno p-value reported

There was a trend that more helical domain PIK3CA mutations were observed in patients with lymph node metastasis staged II∼III, but the difference did not reach statistical significance ( Table S1 in File S1 ).

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