Assessment of Leptin Gene Polymorphism rs2060713 in Psoriasis Vulgaris.

ISRN Dermatol · 2014 · PMC3926229 · PMID 24600521

Europe PMC DOI

hedged sentences

0.1660

closest p · 3.3× alpha

0.4130

boldest claim

The sentences

a weak trendP = 0.166not close (p > 0.1)

We also observed a weak trend of C/T genotype and T allele superiority in late onset female patients ( P = 0.166, OR 4.27; 95% CI: 0.47–38.62 for genotypes and P = 0.176, OR 4.04; 95% CI: 0.46–35.5 for alleles). 4.

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did not reach statistical significanceP = 0.413not close (p > 0.1)

More specifically, within male gender, both genotypes and alleles, in patients versus controls, did not reach statistical significance ( P = 0.413, OR 1.40; 95% CI: 0.62–3.15 for genotypes and P = 0.423, OR 1.38; 95% CI: 0.63–3.06 for alleles).

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an observed trendno p-value reported

An observed trend towards a possible association of this polymorphism with psoriasis' time of onset and/or patient's gender may suggest a possible contribution of the rare allele to particular clinical patterns of the disease.

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