Barely Significant
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Potential for intranasal drug delivery to alter cerebrospinal fluid outflow via the nasal turbinate lymphatics.

Fluids Barriers CNS · 2014 · PMC3927830 · PMID 24528926

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a positive trendno p-value reported
A positive trend of increased CSF absorption with the delivery of NA was observed, however it did not reach statistical significance at any steady-state pressure (Figure 4 B).

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A trend of increased CSF absorption upon noradrenaline delivery was observed: however, this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.